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Overview - Technology
Arrien implements its proprietary and integrated "Fragment-Field Drug Design" - FFDD platform technology to its lead finding discovery workflow on all of its pipeline programs. The key advantage of this platform is for the selection of target-specific lead scaffolds based on the estimated free-energy binding constants and binding patterns. Prior to lead optimization and full-scale Medicinal Chemistry efforts, the pre (clinical) lead scaffolds in complex with the protein targets and their structural knowledge is extensively employed in our early stage of lead identification.
» Scaffold-Based Drug Discovery
» Structure-Based Design Strategies
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